Product Name :
PAX5 Recombinant Rabbit Monoclonal Antibody [6A1]
Predicted band size :
Observed band size :
Synonyms:
B cell lineage specific activator antibody B cell lineage specific activator protein antibody B cell specific activator protein antibody B cell specific transcription factor antibody B-cell-specific transcription factor antibody BSAP antibody EBB-1 antibody KLP antibody Paired box 5 antibody Paired box gene 5 (B cell lineage specific activator protein) antibody 展开
Function :
The human paired box protein Pax-5 (PAX5) is a member of the paired box domain family of transcription factors that play a role in B-cell differentiation, neural development, and spermatogenesis (1).2-Chloro-4-cyclopropylaniline web As a result, its expression is detected in the developing central nervous system (CNS) and testis (1). In particular, PAX5 is essential for maintaining the identity and function of mature B cells during late B lymphopoiesis (2). PAX5 is a B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation (3). During B-cell differentiation, PAX5 interacts with DAXX, a bridge protein that helps PAX5 to function as both a transcriptional activator and a repressor (4). A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia (1).
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse
Verify application:
WB, ICC, IHC-P, FC
Coupling :
unconjugated
Clone number:
6A1
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20 ℃.3,6-Dichloro-2-methoxypyridine Chemical name Stable for 12 months from date of receipt
Storage buffer solution:
1*TBS (pH7.PMID:33749517 4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
45kDa
Positive control :
Ramos, human tonsil tissue.