Product Name :
TXNIP Recombinant Rabbit Monoclonal Antibody [JM60-35]
Predicted band size :
44 kDa
Observed band size :
50 kDa
Synonyms:
EST01027 antibody HHCPA78 antibody THIF antibody Thioredoxin binding protein 2 antibody Thioredoxin interacting protein antibody Thioredoxin-binding protein 2 antibody Thioredoxin-interacting protein antibody TXNIP antibody TXNIP_HUMAN antibody Upregulated by 1,25 dihydroxyvitamin D 3 antibody 展开
Function :
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human TXNIP aa 50-99 / 391.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JM60-35
RRID:
AB_3070602
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.3-(Hydroxymethyl)piperidin-2-one structure 4), 0.Dasatinib Order 05% BSA, 40% Glycerol.PMID:33378755 Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 44 kDa
Positive control :
HeLa cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse stomach tissue lysate, mouse kidney tissue lysate, PC-12, human kidney tissue, mouse kidney tissue, rat kidney tissue, human stomach tissue, mouse esophagus tissue, mouse stomach tissue.