Product Name :
Thymidine phosphorylase Mouse Monoclonal Antibody [A1A8]
Predicted band size :
Observed band size :
Synonyms:
ECGF 1 antibody ECGF antibody ECGF1 antibody Endothelial cell growth factor 1 antibody Endothelial cell growth factor 1 platelet derived antibody Endothelial cell growth factor, platelet-derived antibody Gliostatin antibody hPD ECGF antibody MEDPS1 antibody MNGIE antibody 展开
Function :
Platelet-derived endothelial cell growth factor (PD-ECGF), which is alternatively designated thymidine phosphorylase or gliostatin, is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Biologically active PD-ECGF is a functional dimer that consists of two single polypeptide chains that are expressed in platelets, placenta, foreskin fibroblasts and various squamous cell carcinomas, and they are slowly secreted from the cells. In addition, PD-ECGF is overexpressed in tumor and lesional psoriatic skin and lesional epidermis, indicating that it may play a role in the pathophysiology of psoriasis. Serine residues of PD-ECGF are frequently associated with nucleotide triphosphates, including ATP. In an ATP dependent manner, PD-ECGF is also able to catalyze the reversible phosphorolysis of thymidine to thymine, as it contains thymidine phosphorylase activities.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within human Thymidine Phosphorylase aa 1-200.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
A1A8
RRID:
AB_3071653
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.N-Mal-N-bis(PEG4-NH-Boc) site Aliquot store at -20℃.1256822-12-4 structure Avoid repeated freeze / thaw cycles.PMID:33588666
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
50 kDa
Positive control :
Human lung tissue lysates.