Product Name :
iFluor™ 488 Conjugated pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PDH0-10]

Predicted band size :

Observed band size :

Synonyms:
pan Cytokeratin antibody pan-Cytokeratin antibody pan ck antibody pan-ck antibody panck antibody

Function :
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Since each epithelium contains at least one acidic and one basic keratin, this antibody is used to observe the distribution of keratin-containing cells in normal epithelia and to identify neoplasms derived from such epithelium. Recognizes human cytokeratins 10, 14, 15,16 and 19.

Antibody Type:
Recombinant Mouse Monoclonal Antibody

Immunogen :
Full length native protein corresponding to Human pan Cytokeratin.4-(Benzyloxy)butanoic acid Formula

Species reactivity:
Human

Verify application:
IF-Tissue

Coupling :
iFluor™ 488

Clone number:
PDH0-10

RRID:
AB_3096503

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.731810-57-4 Chemical name Aliquot store at -20℃.PMID:33733926 Avoid repeated freeze / thaw cycles.

Storage buffer solution:
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.

Subtype:
IgG1

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :

Positive control :
Human small intestine tissue, human skin tissue.