Product Name :
3-Formylchromone (CAS 17422-74-1)
Synonym :
4-Oxo-4H-1-benzopyran-3-carboxaldehyde
Application :
CAS:
17422-74-1
Purity:
97%
Molecular Weight:
174.15
Formula :
C10H6O3
Physical state:
Solid
solubility :
Soluble in water (partly).
Shipping Condition :
Store at room temperature
Melting point:
151-153° C (lit.)
SMILES:
C1=CC=C2C(=C1)C(=O)C(=CO2)C=O
References:
:Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products. | Gasparová, R. and Lácová, M. 2005. Molecules. 10: 937-60. PMID: 18007363Biological activity of 3-formylchromones and related compounds. | Kawase, M., et al. 2007. In Vivo. 21: 829-34. PMID: 18019419Synthesis of quinolines from 3-formylchromone. | Plaskon, AS., et al. 2008. J Org Chem. 73: 6010-3. PMID: 18593188Relationship between structure and antioxidative properties of some 3-formylchromone derivatives. | Sersen, F., et al. 2008. Med Chem. 4: 355-7. PMID: 18673147Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors. | Khan, KM., et al. 2009. Bioorg Med Chem. 17: 2983-8. PMID: 193293303-Formylchromones: potential antiinflammatory agents. | Khan, KM., et al. 2010. Eur J Med Chem. 45: 4058-64. PMID: 205763293-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in I kappa B alpha kinase, leading to down-regulation of nuclear factor- kappa B (NF- kappa B)-regulated gene products and sensitization of tumor cells.657408-07-6 Safety Information | Yadav, VR., et al. 2012. J Biol Chem. 287: 245-256. PMID: 22065587Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats.2097518-76-6 manufacturer | Ilamathi, M.PMID:33685900 , et al. 2014. Chem Biol Interact. 219: 175-83. PMID: 249540343-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3. | Ko, JH., et al. 2016. Immunopharmacol Immunotoxicol. 38: 334-43. PMID: 273247223-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in I kappa B alpha kinase, leading to down-regulation of nuclear factor- kappa B (NF- kappa B)-regulated gene products and sensitization of tumor cells. | Yadav, VR., et al. 2016. J Biol Chem. 291: 16926. PMID: 27496967Sulfonyl hydrazones derived from 3-formylchromone as non-selective inhibitors of MAO-A and MAO-B: Synthesis, molecular modelling and in-silico ADME evaluation. | Abid, SMA., et al. 2017. Bioorg Chem. 75: 291-302. PMID: 29065322Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone. | Słomiak, K., et al. 2018. Molecules. 23: PMID: 30126150One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones. | Yuan, J., et al. 2019. Molecules. 24: PMID: 31434258Synthesis of heterocyclic analogs of isoflavone and homoisoflavone based on 3-formylchromone. | Shatokhin, SS., et al. 2021. Russ Chem Bull. 70: 1011-1045. PMID: 34305378NiII and CoII binary and ternary complexes of 3-formylchromone: spectroscopic characterization, antimicrobial activities, docking and modeling studies. | Nabil, N., et al. 2022. RSC Adv. 12: 29939-29958. PMID: 36321099