Pyrophosphatase 1 Recombinant Rabbit Monoclonal Antibody [JE64-39]

Function :
Inorganic pyrophosphatase (or inorganic diphosphatase, PPase) is an enzyme (EC 3.Price of Spiro[3.3]heptan-2-amine hydrochloride 6.1.1) that catalyzes the conversion of one ion of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis, as well as other biochemical transformations.Price of 1190861-74-5 Two types of inorganic diphosphatase, very different in terms of both amino acid sequence and structure, have been characterised to date: soluble and transmembrane proton-pumping pyrophosphatases (sPPases and H(+)-PPases, respectively).PMID:33404136 sPPases are ubiquitous proteins that hydrolyse pyrophosphate to release heat, whereas H+-PPases, so far unidentified in animal and fungal cells, couple the energy of PPi hydrolysis to proton movement across biological membranes.